Collaboration with Merck and Tufts University on Bioreactor Designs

Printing process for cultured meat


Merck, a leading science and technology company, has announced three-year collaborations with theTechnical University of Darmstadt and Tufts University, Massachusetts, USA. The partners want to conduct fundamental research on next-generation, scalable bioreactor designs to support industrial-scale meat and seafood manufacture. Tufts University enables the production of whole muscle cultured meat with textile bioengineering, TU Darmstadt will apply industrial printing technology for the production of textured meat.

While the cultured meat industry is gaining momentum, scaling up the production process and reducing the cost remain key challenges. The primary focus of the collaboration between Merck and the two universities will be the development of next generation, scalable bioreactor designs that can support meat and seafood manufacture on a commercial scale.

“As a leading supplier to the biopharmaceutical industry, we aim to accelerate the emerging cell-based meat industry and become a technology enabler, from R&D to the safe and efficient scale-up of production. The conceptual approaches developed by Tufts University and TU Darmstadt are highly innovative. Both fit our strategy perfectly and complement our internal efforts in the areas of scaffolds, cell differentiation, bioreactors and bioprocess design,” said Thomas Herget, Head of the Silicon Valley Innovation Hub of Merck.

The IDD team will will develop a screen printing process for large-scale production of multi-layered bioink sheets that can be matured into thick, structured meat slices. In contrast to conventional 3D-bioprinting approaches, screen printing enables sheet-to-sheet biofabrication at unmatched production speeds and with ultra-high printing precision.

“In this interdisciplinary project we will first develop a lab-scale printing process and tailor our existing bioink portfolio towards the requirements of meat production. In the next step, we will transfer the concept to an industrial and fully automated printing machine,” Blaeser said. “Our vision is to offer the established technical solution as an open innovation platform for future research on clean meat production. We believe that this approach will not only unite brilliant minds but will also enable leaps in innovation and further accelerate development in this field of research as well as in the related industry.”