Prof. Dr.-Ing. Andreas Blaeser

Head of the BioMedical Printing Technology research group

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Prof. Dr.-Ing. Andreas Blaeser is head of the Department for BioMedical Printing Technology, which was founded in summer 2019. Core of his research is the investigation and development of 3D-bioprinting systems (3D-Bioprinting).

Main focus areas are modelling and experimental research of various mechanisms and phenomena for the transport of biomaterials and their interaction with living cells. The research addresses major biofabrication challenges, such as the parallel printing of multifunctional material composites with different physical, chemical and biological properties. Furthermore, the pre- and post-processing steps accompanying the printing process, 3D data preparation and tissue maturation, are essential research elements.

Bioprinted organs-on-a-chip, which can be used for pharmacological and toxicological screening, as well as bioprinted implants for regenerative medicine provide the application-oriented framework of the department’s research activities. The transfer of the results into clinical practice and into industry is therefore highly relevant. For this reason, scaling and digitization of the investigated biofabrication-methods play an important role (Bioeconomy, IoT, Industry 4.0).

2019 – today Professor for BioMedical Printing Technology, TU Darmstadt
2019 Theodore von Kármán Fellowship, University of California, Los Angeles (USA)
2018 – 2019 Head of the research group Medical Textiles & Biofabrication at Institut für Textiltechnik of RWTH Aachen University
2017 Founder of Black Drop Biodrucker GmbH
2012 – 2017 Doctorate (Dr.-Ing.) and then Post-Doc at RWTH Aachen University
2011 Research stay at Imperial College London (England)
2006 – 2012 Studies of Mechanical Engineering (B.Sc.) at DHBW Mannheim and then studies of Biomedical Engineering (M.Sc.) at RWTH Aachen University

Selected Publications

2019 Duarte Campos DF, Bonnin Marquez A, O’Seanain C, Fischer H, Blaeser A, Vogt M, Corallo D, Aveic S. Exploring Cancer Cell Behavior In Vitro in Three-Dimensional Multicellular Bioprintable Collagen-Based Hydrogels. Cancers, 2019, 11:180.

2018 Goetzke R, Franzen J, Ostrowska A, Vogt M, Blaeser A, Klein G, Rath B, Fischer H, Zenke M, Wagner W. Does soft really matter? Differentiation of induced pluripotent stem cells into mesenchymal stromal cells is not influenced by soft hydrogels, Biomaterials, 2018, 156:147-158.

2018 Glimpel N, Bolle T, Gries TG, Blaeser A. Bewegung in die Arthrosebehandlung bringen : Abstandsgewirke als Gewebeersatz in der Transplantationsmedizin. Kettenwirk-Praxis 2018, 52:30-31.

2018 Eickhoff R, Bolle T, Kossel K-M, Heise D, Kroh A, Lambertz A, Blaeser A, Jockenhövel S, Gries T, Neumann UP, Klink CD. Improved Biocompatibility of Profiled Sutures through Lower Macrophages Adhesion. J Biomed Mater Res B Appl Biomater 2018, doi: 10.1002/jbm.b.34269.

2018 Idrissi A, Granich D; Gries T; Blaeser A: Development of a textile-integrated, multimodal sensor device for biosignal acquisition, Biomedical Engineering, 2018, 63, S. S278.

2017 Forget A*, Blaeser A* (shared first), Miessmer F, Köpf M, Duarte Campos DF, Voelcker NH, Blencowe A, Fischer H, Shastri VP: Mechanically Tunable Bioink for 3D Bioprinting of Human Cells. Adv Healthc Mater 2017, 1700255:1700255.

2017 Blaeser A, Duarte Campos DF, Fischer H. 3D bioprinting of cell-laden hydrogels for advanced tissue engineering. Curr Opin Biomed Eng 2017, 2:58-66.

2016 Blaeser A, Million N, Duarte Campos DF, Gamrad L, Köpf M, Rehbock C, Nachev M, Sures B, Barcikowski S, Fischer H: Laser-based in situ embedding of metal nanoparticles into bioextruded hydrogel tubes enhances human endothelial cell adhesion. Nano Res. 2016, 9:3407–3427.

2016 Blaeser A, Duarte Campos DF, Puster U, Richtering W, Stevens MM, Fischer H. Controlling Shear Stress in 3D Bioprinting is a Key Factor to Balance Printing Resolution and Stem Cell Integrity. Adv Healthc. Mater. 2016, 5:326-33.

Patents

2017 Blaeser A. Verfahren zur Herstellung einer dreidimensionalen biologischen Struktur und diese Struktur so erhaltend. DE 10 2017 120 470.9. Prioritätsdatum: 06.09.2017.

2017 Forget A, Blaeser A, Fischer H, Shastri P. Mechanically tunable bioinks for bioprinting. EP17181083.1. Prioritätsdatum: 12.07.2017.

2014 Blaeser A, Theek B, Lammers T, Kiessling F and Fischer H. Gewebemodell und Verfahren zum Herstellen hiervon sowie dessen Verwendung. 2014070410553600DE. Prioritätsdatum: 04.07.2014.

2012 Duarte Campos DF, Blaeser A, Weber M, Neuss S, Jahnen-Dechent W and Fischer H. Verfahren zum Herstellen dreidimensionaler Strukturen und solche Strukturen. DE 10 2012 100 859.0. Prioritätsdatum: 02.02.2012.